摘要
目的观察沙利度胺联合复方氟米松软膏治疗结节性痒疹疗效。方法将87例结节性痒疹患者随机分为两组。治疗组45例,口服沙利度胺50mg,2次/d,症状改善后逐步减量50mg或25mg,1次/d维持,联合外用复方氟米松软膏,1次/d,共8周;对照组42例,口服左西替利嗪片5mg,1次/d,联合外用复方氟米松软膏1次/d,共8周。结果治疗组有效率为91.11%,对照组为69.05%,两组有效率差异有统计学意义(P<0.05),均无明显不良反应。结论沙利度胺联合复方氟米松软膏治疗结节性痒疹安全可靠。
Objective To observe the clinical efficacy of combination of thalidomide and flumetasone ointment in the treatment of prurigo nodularis. Methods Eighty-seven patients were randomly divided into two groups. 45 pa- tients in the treatment group were treated with thalidomide and flumetasone ointment for 8 weeks. Initial dose of thalido- mide is 50rag twice a day, and the dose is reduced to 50rag or 25rag once a day when symptoms are improved gradually. Flumetasone ointment is administrated once a day. Forty-two patients in the control group were treated with levoeetirizine and flumetasone ointment for 8 weeks. The dose of is levocetirizine 5mg once a day, and flumetasone ointment is admin- istrated once a day. Results After 8 weeks, the effective rates of treatment group was 91.11%, and the control group was 69.05 %. There was statistical significance between the two groups （P 〈 0. 05 ）. Conclusion It was safe and relia- ble to treat prurigo nodularis with combination of thalidomide and flumetasone ointment.
出处
《中国医学文摘（皮肤科学）》
2014年第6期339-340,共2页
China Medical Abstracts(Dermatology)
