伴有腔隙性脑梗死的突发性聋患者的临床分析

Clinical analysis of sudden deafness patients with lacunar infarction

目的:探讨伴有腔隙性脑梗死(腔梗)的突发性聋患者的治疗效果及预后。方法:回顾性分析我院2007至2012年96例突发性聋患者的临床资料,影像学检查(头颅CT或MRI)有腔梗者为腔梗组(n=38),无腔梗者为非腔梗组(n=58)。两组均给予激素,扩张血管、营养神经药及高压氧综合治疗,疗程为10 d,治疗前后行纯音测听检查,观察两组疗效差别并分析其相关影响因素。结果:腔梗组治疗总有效率为39.5%,非腔梗组治疗总有效率为50%,两组疗效差异无统计学意义(P>0.05)。结论:综合方案对伴有腔梗或不伴腔梗的突发性聋患者的疗效相仿。

Objective： To explore the treatment effect and prognostic factors of sudden deafness patients with lacunar infarction. Methods： The data of 96 patients with sudden deafness who were examined by computed tomography （CT） or MRI in our hospital from 2007 to 2012 were retrospectively analyzed. The lacunar infarction group was defined as the patients who had cavernous space cerebral infarction. Non lacunar cerebral infarction group was defined as the patient with normal cranial imagings. Both groups were treated comprehensively including corticosteroids, vasodilators, neurotrophic drugs and hyperbaric oxygen therapy. The treatment last for 10 days. Both groups were given pure tone audiometry before and after the treatment. Results： The effective rate of the lacunar infarction group was 39. 5%, while that of the non lacunar cerebral infarction group was 50%. The difference of effective rate between the two groups was not statistically significant （P 〉 0. 05 ）. Conclusion： There is no difference in efficacy of the treatment between sudden deafness patients with lacunar infarction and without cavernous space cerebral infarction.