残余尿对良性前列腺增生症患者血清前列腺特异性抗原的影响

The influence of post-void residual volume on prostate specific antigen in patients with benign prostatic hyperplasia

目的 研究残余尿对良性前列腺增生症（BPH）患者血清前列腺特异性抗原（PSA）的影响.方法 将接受前列腺手术治疗,术后病理为BPH的患者160例分成无残余尿（残余尿＜60 ml）组40例,少量残余尿（60 ml≤残余尿＜120 ml）组40例,中量残余尿（120 ml≤残余尿＜180 ml）组40例,大量残余尿（残余尿≥180 ml）组40例,比较四组患者血清PSA水平.结果 大量残余尿组PSA[（8.52 ±6.72）μg/L]明显高于无残余尿组[（5.26±4.16） μg/L]和少量残余尿组[（5.93±5.20）μg/L],差异有统计学意义（P＜0.05）,无残余尿组与少量残余尿组PSA比较差异无统计学意义（P＞0.05）.结论 无残余尿对BPH患者血清PSA水平无影响,大量残余尿可使血清PSA水平显著升高.

Objective To study the influence of post-void residual volume on prostate specific antigen （PSA） in patients with benign prostatic hyperplasia （BPH）.Methods One hundred and sixty BPH patients who diagnosed by postoperative pathologic manifestations were selected.The patients were divided into 4 groups according to post-void residual volume with 40 cases each：non post-void residual volume （post-void residual volume 〈 60 ml） group,less post-void residual volume （60 ml≤post-void residual volume 〈 120 ml） group,middle post-void residual volume （120 ml ≤post-void residual volume 〈 180 ml） group,mass post-void residual volume （post-void residual volume ≥180 ml） group.The serum PSA levels of 4 groups were observed.Results The PSA level in mass post-void residual volume group [（8.52 ± 6.72） iμ g/L] was significantly higher than that in non post-void residual volume group [（5.26 ± 4.16） μ g/L] and less post-void residual volume group [（5.93 ± 5.20） μ g/L],there were statistical differences （P 〈 0.05）,there was no statistical difference between non post-void residual volume group and less post-void residual volume group （P 〉 0.05）.Conclusions The serum PSA level in BPH patients with non post-void residual volume has no change,while the serum PSA level in BPH patients with mass post-void residual volume is significantly elevated.