期刊文献+

血清中TPOAb和TgAb的升高对甲状腺疾病进展的影响 被引量:4

下载PDF
导出
摘要 目的研究健康人群血清中抗甲状腺过氧化物酶抗体(TPOAb)和(或)抗甲状腺球蛋白抗体(TgAb)升高对甲状腺疾病进展的影响。方法从2011年1月1日至2013年12月31日对48例健康人的甲状腺功能进行跟踪调查,采用全自动化学发光免疫分析法(CLIA)检测其促甲状腺激素(TSH)、TPOAb和TgAb水平。结果 48例中有4例最终发展成甲亢,9例发展成为桥本甲状腺炎。结论血清中TPOAb和TgAb的升高在一定程度上影响了甲状腺疾病的发展,需要引起必要的重视。
出处 《国际检验医学杂志》 CAS 2014年第24期3433-3434,共2页 International Journal of Laboratory Medicine
  • 相关文献

参考文献5

二级参考文献25

  • 1[1]Colin M, Dayan, Cilbert HD, et al. Chronic autoimmune thyroiditi[J]. N Engl J Med, 1996,335(1) :99
  • 2[2]Weetman AP, Mcyregor. Autoimmune thyroid disease: fur ther developments in our understanding[J]. Endocrine Rev, 1994,15(3) :788
  • 3[3]Nordvka RA, Gilber FI, Mattyhys P, et al. The superiority of antimicrosome over antithyroglobulin antibody for de tecting Hashimoto's thyroiditis [J ]. Arch Intern Med, 1993,153 (1): 862
  • 4[4]Macht L,Fukuma N,Denet C, et al. Severe combined im munodeficient(SCIP) mice: a modal for investigating hu man thyroid autoantiboly synthesis[J ]. Clin Exp Immunol, 1991,84(1):34
  • 5[5]Kohno Y, Yarnaguchi F. Anti-thyroid peroxidase antibodies in sera from healthy subjects and from patients with chronic thyroiditis:differentes in the ability to inhibit thy roid peroxidase activity[J]. Clin Exp Immunol, 1999,85 (2):459
  • 6[6]Rieum Richand A, Shinitzhy M, Wada H, et al. Effects of thyroid status on thyroid autoimmunity expression in en thyroid and hypothyroid patients with Hashimoto's thy roiditis[J ]. Clin Endocrinol(oxf), 1994,40(3) :529
  • 7[7]Cliovato L, Pinchera A. The microsomal/peroxidase anti gen: modulation of its expression in thyroid disease[J]. Au toimmunity, 1991,10(2) :319
  • 8[8]Mandel SJ, Brent GA, Georgee HI, et al. Levothyroning therapy in patients with thyroid disease [J]. Ann Inter Med, 1993,119(3):480
  • 9[9]Vanderpump MPJ, Tunbridgo WMC. The incidence of thyroid disorders in the community: a twenty year follow up of the whickham survey[J]. Clin Endocrinol (oxf), 1995,43(1):55
  • 10[10]Feldt RU, Hermaden M, Semple GW, et al. Anti-thy roid peroxidase antibodies in thyroid disorders and non thyroid autoimmune disease[J]. Autoimmunity, 1991,3 (1):245

共引文献71

同被引文献36

二级引证文献83

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部