1例小儿神经母细胞瘤患者术后化疗的药学监护

Pharmaceutical Care for a Child with Neuroblastoma Postoperative Chemotherapy by Clinical Pharmacists

目的:探讨对神经母细胞瘤患儿实施药学监护的内容和意义。方法:临床药师通过对1例5岁儿童神经母细胞瘤术后进行奥沙利铂联合依托泊苷化疗的全程药学监护,以化疗药物合理应用、不良反应监测和预防、个体化用药方案的制定作为临床药师药学监护切入点。结果:临床药师通过医嘱审核发现并及时纠正错误,并对患儿实施骨髓抑制、神经毒性、消化道反应等不良反应的预防与监护,使患儿顺利度过了化疗期。结论:实施药学监护的过程中,临床药师及时有效的建议促进了肿瘤化疗患儿的合理用药。

Objective： To investigate the content and meaning of pharmaceutical care in children with neuroblastoma. Methods：Clinical pharmacists participated in the entire pharmaceutical care process of a five-year-old child with neuroblastoma postoperative chemotherapy of oxaliplatin combined with etoposide,rational use of chemotherapy drugs,monitoring and prevention for adverse drug reaction and personalized medicine regimen as the breakthrough point. Results： Pharmacist can rectify irrational medications in time by examining prescriptions,and help this child successfully through the period of chemotherapy by preventing and monitoring adverse drug reactions such as myelosuppression,neurotoxicity and digestive tract reactions. Conclusion： Clinical pharmacists promote the safety and efficacy of drug use in children with malignancy chemotherapy by timely and effective suggestion in entire pharmaceutical care process.