丁二酸铵水溶液直接酯化合成丁二酸酯

Synthesis of succinic acid ester by direct esterification of ammonium succinate solution

以NH4HSO4为催化剂,正丁醇为酯化剂,丁二酸铵水溶液为原料制备丁二酸单丁酯和丁二酸二丁酯。考察反应温度、反应时间、催化剂用量和醇铵摩尔比等因素对酯化反应的影响,得到较佳的酯化反应工艺条件:丁二酸铵溶液质量分数50%,醇铵摩尔比5,反应时间8 h,反应温度130℃,催化剂用量为5%(按丁二酸铵质量计),丁二酸丁酯的总收率可达83.2%。

Succinic acid esters were prepared by ammonium succinate solution and n-butanol using ammonium hydrogen sulfate as catalyst. The effects of ammonium succinate concentration,ratio of nbutanol to ammonium succinate,catalyst dosage,reaction temperature and reaction time on esterification yield were investigated. Results showed that optium reaction conditions were as follows： ammonium succinate concentration of 50%,the molar ratio of n-butanol to ammonium succinate of 5,catalyst dosage of 5%（ mass of ammonium succinate）,reaction temperature of 130 ℃,and reaction time of 8 h. The total yield of esterification could reach 83. 2%.