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miRNA靶标及Poly-miRTS预测软件的研究进展 被引量：1

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摘要 1 miRNA的靶标预测方法 微小RNA（miRNA）基因在RNA聚合酶Ⅱ的作用下形成500~3 000nt的原始miRNA转录产物（pri-miRNA）,在细胞核内pri-miRNA被RNaseⅢDrosha及辅助因子Pasha作用进一步剪切为60~70nt的precursor miRNA（pre-miRNA）.pre-miRNA在Exportin5/Ran-GTP的协同作用下通过核孔复合体运送到细胞质中进一步被Dicer酶剪切为22nt左右的非编码单链小RNA．
作者 崔明花 金光
机构地区 延边大学医学院病理学教研室
出处 《延边大学医学学报》 CAS 2014年第3期224-227,共4页 Journal of Medical Science Yanbian University
关键词 MIRNA Poly-miRTS 靶标 预测软件
分类号 Q75 [生物学—分子生物学]
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参考文献24

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二级参考文献30

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共引文献16

同被引文献10

引证文献1

二级引证文献3

延边大学医学学报
2014年 第3期

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