解毒扶正颗粒联合化疗治疗晚期非小细胞肺癌的临床研究

The Clinical Study of Jiedufuzheng Granules Combined with Chemotherapy in Patients with Advanced Non-small Cell Lung Cancer

目的：探讨解毒扶正颗粒联合化疗治疗晚期非小细胞肺癌的临床疗效。方法：选取我院肿瘤科2012年1月-2013年12月收住院的晚期非小细胞肺癌患者60例,随机分为观察组与对照组各30例,对照组患者采用单纯化疗的方法 ,观察组患者予以解毒扶正颗粒联合化疗,治疗2个周期后比较两组患者的治疗效果。结果：在近期治疗效果方面,观察组明显优于对照组,且差异明显（P〈0.01）;在各免疫指标方面,观察组均优于对照组,且差异明显（P〈0.05）;在不良反应方面,观察组明显低于对照组,且差异明显（P〈0.01）。结论：解毒扶正颗粒联合化疗治疗晚期非小细胞肺癌效果明显,可提高患者治疗后的生活质量,提高免疫功能,降低毒副作用,延长患者的生存时间,值得临床上进一步推广应用。

Objective： To explore the efficacy of Jiedufuzheng g ranules combined with chemotherapy in patients with advanced non-small cell lung cancer. Methods： 60 Patients who were selected from the oncology department of our hospital from January 2012 to December 2013 were randomly assigned to observation group and control group, every group had 30 patients, the control group, the observation group was treated by Jiedufuzheng granules and chemotherapy, compared the efficacy between the two groups after 2 courses.Results： In the short term effectiveness, the observation group was better than the control group, and the difference was statistically significant（P〈0.01）; in all immune parameters, the observation group was also better than the control group, and the difference was statistically significant（P〈0.05）; the adverse reactions in th e observation group wassignificantlylower than that in the control group（P〈0.01）.Conclusion： Jiedufuzheng granules combined with chemotherapy have good effect in patients with advanced non-small cell lung cancer,can improve patients＇ quality of life, can improve immune function, can reduce toxicity, and can prolong survival time, so it is worthy to promote in clinical practice.