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PI3K/Akt/mTOR信号通路在晚期或复发子宫内膜癌靶向治疗中的研究进展 被引量:1

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摘要 子宫内膜癌是常见的女性恶性生殖道肿瘤,其晚期或复发患者的预后仍然较差。近些年新出现的靶向治疗已成为晚期或复发子宫内膜癌的重要治疗手段。PI3K/Akt/mTOR信号通路在子宫内膜癌的发生发展过程中起着重要的调节作用,抑制该通路有效位点的靶向治疗可能提高晚期或复发子宫内膜癌的治疗效果。但目前针对该信号通路的药物研究仍处于初步阶段,仍需要更多的临床试验加以明确疗效。
作者 舒桐 白萍
出处 《癌症进展》 2014年第5期457-463,共7页 Oncology Progress
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