转移型中央区淋巴结微小乳头状甲状腺癌手术效果及高危因素分析

Operation Effect and Risk Factors of Transfer Type Papillary Thyroid Microcarcinoma with Lymph Node in Central Region

目的探讨腔镜手术治疗甲状腺微小乳头状癌(papillary throid microcarcinoma,PTMC)临床疗效和中央区淋巴结转移的高危因素。方法对80例经腔镜手术治疗的PTMC临床资料进行回顾性分析,并采用SPSS统计软件分析中央区淋巴结转移的高危因素。结果术后有1例出血现象,无饮水呛咳、皮下气肿、甲状旁腺功能永久低下等并发症出现,影像学检查发现无残留腺体存在,并且局部无复发迹象,恢复状况良好;Logistic回归分析发现,年龄、性别、肿瘤直径、包膜外侵、肿瘤分布位置是引起中央淋巴结转移的危险因素,似然以(odd ratio,OR)=2.186、1.357、2.608、1.792、1.531(P<0.05或0.01)。结论 PTMC采用腔镜手术治疗临床效果显著。

Objective To study the clinical curative diect of surgical treatment ol papillary myrold mlcrocarcmom （PTMC） and the risk factors of lymph node metastases in central region.Methods The clinical data of 80 cases accepting surgical treatment of the PTMC were retrospectively analyzed.The risk factors of lymph node metastases in central region were analused using SPSS.Results Postoperative bleeding was ohserved in 1 case.No water choke,subcutaneous emphyse ma,low parathyroid function permanent complications were observed.Imaging examination showed no residual gland and no sign of recurrence.The restore condition was good. Logistic regression analysis found that age, gender, tumor diameter distribution, the capsule invasion, tumor location were the risk factors for lymph node metastasis, （odd ratio, OR） = 2.186, 1.357,2.608,1.357,2.608 （P〈0.05 or 0.01）.Conclusion The clinical effect of surgical treatment on PTMC is remarka ble.Age, sex, tumor size,capsule invasion,mass distribution location are the important factors affecting the central lymph node metastasis.