摘要
近红外化学成像是一门新兴的中药关键质量属性快速分析技术。它将传统近红外光谱技术与化学成像技术相结合。本文简要介绍了近红外化学成像可视化的核心部件;重点阐述高维数据可靠性获取、转化、分析及应用;综述了近红外化学成像在制药领域的应用研究,分析了近红外成像技术应用于中药质量控制领域所面临的机遇与挑战。
Near infrared chemical imaging （NIR-CI） is an emerging technology for rapidly analyzing the critical quality attribute of Chinese materia medica （CMM）. It integrates NIR spectroscopy with chemical imaging. In this paper, it provided a systematic introduction to NIR-CI, such as the core part of instrument, the reliability, transformation, analysis and application of high-dimensional data acquisition. In addition, current studies of NIR-CI application in pharmaceutical field were analyzed. Finally, future opportunities and challenges of NIR -CI applications in the quality control of CMM preparation were prospected.
出处
《世界科学技术-中医药现代化》
北大核心
2014年第12期2568-2574,共7页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家自然科学基金委青年基金项目(81303218):多源信息融合的中药近红外模型适用性评价方法研究
负责人:吴志生
国家中医药管理局行业专项(201407003):NIR模型群的金银花与山银花质量快速可靠性评价研究
负责人:吴志生
关键词
近红外化学成像
过程分析技术
中药关键质量属性
可视化
图像分析
Near-infrared chemical imaging
process analysis technology
critical quality attributes of Chinese materia medica
visualization
image analysis
