2004-2012年南京市秦淮区梅毒流行病学特征分析

The analysis and control strategy study on epidemiology of syphilis in Qinhuai District from 2004 to 2012

目的 ：了解南京市秦淮区2004-2012年梅毒的流行病学特征,为制定梅毒及性病预防控制策略提供依据。方法 ：收集全区通过中国疾病预防控制信息系统报告的梅毒疫情资料,使用Excel 2003、SPSS16.0进行统计学分析。结果：2004-2012年,秦淮区共报告梅毒1 310例,发病数从2004年开始不断增高,2010年开始下降,年均报告病例增长率为4.00%,年均报告发病率增长率为3.22%。在报告的梅毒病例中,以早期显性（一、二期）梅毒为主,占71.53%,从历年梅毒病例报告构成比来看,一期梅毒在持续下降,而隐性梅毒比例不断升高,各年度梅毒病例分期之间有显著差异（P〈0.05）。梅毒男女性别比为0.91∶1.00,除2005年外其他各年梅毒病例性别之间差异无显著性。梅毒的发病年龄集中在20-39岁年龄组,共676例,占51.60%。结论：秦淮区梅毒发病率从2004年开始逐年升高,2010年后开始下降,但显性梅毒所占比例很大,提示秦淮区梅毒疫情上升的风险仍然很高,所以应进一步加强性病艾滋病综合防治措施,规范梅毒诊治,控制梅毒流行,从而控制性病艾滋病的快速传播。

Objective：To analyze the epidemiological characteristics of syphilis in Qinhuai district of Nanjing,Jiangsu province from 2004 to 2012. Methods：The epidemic data of syphilis from China disease prevention and control information system in Qinhuai district was analyzed by excel 2003 and SPSS 16.0. Results：There were reported a total of 1310 cases of syphilis in Qinhuai distict from 2004 to 2012. In the reported cases of syphilis,early syphilis including primary and secondary syphilis were 71.53%; there were significant differences between the stages of syphilis cases and the different years（P〈 0.05）; the gender ratio was 0.91 ∶1.00; there were 676 cases of syphilis were aged from 20 to 39,accounting for 51.60% in total cases of syphilis. Conclusion：The incidence of syphilis in Qinhuai distict was increased from 2004,declined from 2010,and most of cases of syphilis were primary and secondary syphilis,we should strengthen the comprehensive measures of prevention diagnosis and treatment of syphilis,in order to control the spread of syphilis and AIDS.