吉林市地区9735例人群骨密度调查及骨质疏松发病率分析

Investigation and analysis of incidence of osteoporosis for 9735 cases of bone mineral density population in Jilin city region

目的调查吉林市地区9735例健康人群的骨密度,分析本地区峰值骨量、骨密度变化规律及骨质疏松发病率。方法采用法国MEDILINK公司OSTEOCORE-2双能X线骨密度检测仪,检测受试者非受力侧前臂尺桡骨远端1/3的骨密度。按性别、相差5岁为一年龄段分组,应用SPSS 16.0软件对骨密度变化规律、峰值骨量、骨质疏松发病率等进行统计学分析。结果吉林市地区男性与女性峰值骨量均在30~39岁年龄段出现,男性为（0.6271±0.04791）g/cm2,女性为（0.5169±0.04584）g/cm2。骨密度丢失率：女性50岁后、男性60岁后增加。骨质疏松症发病率：女性50岁后、男性70岁后明显增加。女性各年龄段发病率均高于男性,差异显著（P〈0.05）。结论吉林市地区男性和女性峰值骨量均在30~39岁出现,不同年龄、性别骨密度丢失率及骨质疏松患病率差异较大。

Objective To investigate bone mineral density（BMD） of 9735 cases of healthy people and analyze their peak bone mass, the change rule of BMD as well as in Jilin city region the incidence of osteoporosis. Method Used OSTEOCORE-2 dual-energy X-ray absorptiometry detector of MEDILINK French company detecting patients＇ BMD of the stress lateral forearm foot radius distal 1/3. Divided patients into different groups by gender and age with 5-year-old difference. Used SPSS 16.0 software to analyze bone density variation, peak bone mass and the incidence of osteoporosis. Result Peak bone mass of Jilin city region appeared at age 30 ~ 39 years old, male peak bone mass was（0.6271±0.04791） g/cm2, female peak bone mass was（0.5169±0.04584） g/cm2. BMD loss rate： after the age of 50 female began to lose BMD, while BMD loss rate of male after a 60-year-old began to increase. The incidence of osteoporosis： after the age of 50 female had high incidence of osteoporosis, while male got significantly high incidence of osteoporosis at the age after 70-year-old. The morbidity of female was higher than male, and the differences between two groups were significant（P〈0.05）. Conclusion Peak bone mass of both female and male in Jilin city region appeare at the age of 30 ~ 39 years old, BMD loss rate and the morbidity of osteoporosis are quite different among different age and gender.