菖远汤干预老年慢性稳定性心绞痛患者血管弹性的疗效观察

Effect Observe of the Elasticity of the Blood Vessels of Elderly Patients with Chronic Stable Angina Treated with Changyuan Decoction

目的 :观察菖远汤干预老年慢性稳定性心绞痛痰瘀阻络型患者血管弹性的疗效。方法 :将符合研究标准的60例患者分为治疗组和对照组各30例,对照组给予常规西药治疗;治疗组在对照组用药基础上加菖远汤。比较用药前后两组间疗效、踝-臂脉搏波传导速度(ba PWV)、大动脉弹性指数(C1)和小动脉弹性指数(C2)和血脂水平的差异。结果:治疗8周后,治疗组疗效高于对照组(P<0.05);治疗组的ba PWV明显为小(P<0.05),C1、C2明显为大(P<0.05);治疗组高密度脂蛋白胆固醇水平明显高于对照组(P<0.05)。结论:菖远汤在疗效和改善老年慢性稳定性心绞痛痰瘀阻络型患者的血管弹性功能方面有较好疗效。

Objectives：To observe the effect of changyuan decoction in improving the vascular elasticity of elderly patients with chronic stable angina. Methods ：The patients meeting the criteria for research were divided into treatment group and control group. The control group was treated with routine western medicine, while the treatment group was treated with routine western medicine and changyuan decoction. Then the difference of the effect,brachial-ankle pulse wave velocity（baPWV）,artery elasticity index（C1） and small artery elastic- ity index（C2）,and the blood lipid level between the two groups were compared. Results：There 60 cases completing the experiment,with the rate of lost to follow-up 4.76%. Through the comparison,it was found that 8 weeks after the treatment,compared with the control group, in treatment group, the total effective rate was high（P〈0.05）,the baPWV was small（P〈0.05）,Cland C2 were low（P〈0.05）,and the high-density lipoprotein cholesterol level was significantly higher than that of the control group（P〈0.05）. Conclusions： Changyuan decoction has obvious advantage in curative effects and the improvement on the vascular elasticity of elderly patients with chronic stable angina of phlegm and stasis blocking collaterals.