摘要
角膜基质层是构成角膜的主要结构,近年来对角膜基质层结构的研究主要采用X线衍射、电子显微镜及非线性光学技术.研究者利用这些技术,从轴方向和子午线方向上探究角膜基质层胶原纤维的分布规律,从而探讨这些分布规律与角膜基质层力学特性关系.研究表明,临床上常见的角膜扩张症（如圆锥角膜、准分子激光原位角膜磨镶术术后角膜扩张症）也被证实与病变角膜的结构改变导致力学特性改变有关.利用这一结果,研究者积极探讨治疗这类角膜扩张症的方法.
Corneal stroma is the primary structure of cornea.The common technologies in studying the structure of corneal stroma are X-Ray scattering,electron microscopy and nonlinear optical imaging （NLO）.By these techniques,researchers try to find the distribution rule of collagen fibers along axial and meridian direction and to find the relation between the mechanical property and the rules.It is proved that corneal ectasia,such as keratoconus and post-LASIK ectasia,is induced by the change of coneal mechanical property,which is caused by the change of corneal structure.Researchers are trying to find methods to treat these corneal ectasia.
出处
《国际眼科纵览》
2014年第6期361-365,共5页
International Review of Ophthalmology
基金
国家自然科学基金（11372011）
北京市自然科学基金（7142159）
