立体定向血肿抽吸术联合药物治疗抗血栓药物所致脑出血观察

Effect of Stereotactic Aspiration Combined with Drug Therapy in the Treatment of Cerebral Hemorrhage Induced by Antithrombotic Drugs

目的:观察立体定向血肿抽吸术联合药物治疗抗血栓药物所致脑出血的临床疗效。方法:66例因抗血栓药物致脑出血患者随机分为对照组与观察组各33例。对照组根据患者脑出血致病原因采用对应药物治疗;观察组在对照组基础上再给予立体定向血肿抽吸术治疗。比较两组患者治疗前、后日常生活能力、神经功能缺损评分(NIHSS)及预后改善等情况。结果:治疗后,观察组NIHSS评分为(10.17±2.97)分,Barthel指数评分为(59.97±12.10)分,均明显优于对照组(P<0.05)。且观察组预后有效率也明显高于对照组(P<0.05)。两组患者均未发生严重不良反应。结论:针对不同药物致脑出血患者采用对应药物治疗,并实施立体定向血肿抽吸术治疗,可有效改善患者神经功能缺损和日常生活能力,进而改善患者预后,且较为安全。

Objective： To observe the effect of stereotactic aspiration combined with corresponding drug therapy in the treatment of cerebral hemorrhage induced by different drugs. Methods： Totally 66 patients with hemorrhage induced by antithrombotic drugs were randomly divided into the control group and the treatment group with 33 cases in each. The control group was given corresponding drug therapy according to the pathogenesis of cerebral hemorrhage,and the treatment group was treated by stereotactic hematoma aspiration additionally. Daily life ability,NIHSS and prognosis improvement were compared between the two groups before and after the treatment. Results： After the treatment,NIHSS of the treatment group was（ 10. 17 ± 2. 97） and Barthel index score was（ 59. 97 ±12. 10）,which were both better than those of the control group（ P 0. 05）. The prognosis of the treatment group was also better than that of the control group（ P 0. 05）. There was no severe adverse drug reaction in the two groups. Conclusion： For different drug induced cerebral hemorrhage,corresponding drug therapy should be carried out,and combining with stereotactic hematoma aspiration,the therapeutic regimen can effectively improve neurological deficits and activities of daily living of the patients,and then improve the prognosis of the patients with promising safety.