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大庆地区4850例育龄妇女宫颈癌筛查结果的临床分析 被引量:13

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摘要 目的:了解大庆地区宫颈癌发病的高危因素,探讨宫颈液基细胞学(TCT)联合高危型人乳头状瘤病毒(HPV)检测在宫颈癌及癌前病变筛查中的诊断价值。方法:对大庆地区4 850例育龄妇女进行宫颈TCT联合HPV检测,对TCT和/或HPV检测异常者进行阴道镜下宫颈组织多点活检病理学检查。结果:1 193例TCT结果异常,行阴道镜下活检病理发现CINⅠ~Ⅲ501例(41.99%);HPV检测阳性1 875例,行阴道镜下活检病理发现CINⅠ~Ⅲ1 030例(54.93%);HPV和TCT均阳性684例,行阴道镜检查活检发现CINⅠ~Ⅲ625例(91.37%),各组间比较,差异有统计学意义(P〈0.05)。1 875例HPV阳性患者检测结果随着年龄增长而逐渐降低,以20~30岁为感染的最高峰。结论:宫颈TCT检测联合高危型HPV检测可有效提高宫颈病变的诊断率,是宫颈病变早期筛查的有效手段,应全面推广。
出处 《中国妇幼保健》 CAS 2015年第6期844-846,共3页 Maternal and Child Health Care of China
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