自拟中药汤剂联合西药治疗紧张型头痛疗效分析及不良反应观察

Effect of Self-made Decoction Combined with Western Medicine Treatment of Tension-Type Headache and Adverse Reactions

目的:探讨自拟中药汤剂联合西药治疗紧张型头痛疗效分析及不良反应观察,为临床诊断治疗提供参考。方法:将本组500例紧张型头痛患者按照随机数字表法将其随机分为对照组(n=250)和观察组(n=250);对照组给予盐酸阿米替林片治疗,治疗组在对照组治疗基础上服用中药自拟汤剂;两组治疗均以3周为1个疗程。结果:治疗组治疗后总有效率(95.20%)显著高于对照组(70.80%),且有显著性差异(P<0.05);治疗组轻度疼痛患者显著多于对照组,且有显著性差异(P<0.05);治疗组中度疼痛和重度疼痛均显著少于对照组,且有显著性差异(P<0.05);两组患者均无明显不良反应发生。结论:自拟中药汤剂联合西药治疗紧张型头痛疗效显著,且无明显不良反应发生,具有重要的临床研究价值,值得推广。

Objective： To investigate the efficacy of self- made decoction combined with western medicine treatment of tension- type headache and adverse reactions and to provide a reference for clinical diagnosis and treatment. Methods：500 cases of patients with tension- type headache,according to the random number table,were randomly divided into control group（ n = 250） and observation group（ n = 250）. The amitriptyline hydrochloride tablets were given to the control group and the treatment group on the basis took self- made decoction treatment and three weeks was as a course. Results：After treatment,the treatment group＇s total efficiency（ 95. 20%） was significantly higher than that of the control group（ 70. 80%） and there was a significant difference（ P〈 0. 05）. The treatment group＇s patients with mild pain were significantly more than those of the control group and there was a significant difference（ P 〈0. 05）. The treatment group with moderate pain and severe pain were significantly fewer than those of the control group and there was a significant difference（ P 〈0. 05）. Two patients had no significant adverse reactions. Conclusion： Self- made decoction combined with western medicine treatment of tension- type headache has significant effect and no significant adverse events. The clinical research has important value and it is worthy of promotion.