加味生化汤治疗产后并发症的临床研究

Clinical Study of Modified Biochemical Decoction in the Treatment of Postpartum Complications

目的:分析加味生化汤对产妇血液流变学指标和产后并发症的影响,以探讨其在产后工作中的应用价值。方法:选取医院阴道分娩产妇316例,以随机数字表分为两组(n1=n2=158);对照组产妇产后行手法按摩,观察组在此基础上产后给予加味生化汤。对比两组患者的产后并发症发生情况;同时,分别于治疗人员前后抽取患者空腹静脉血,采用全自动血液流变分析仪分析全血高切黏度(HBV)、低切黏度(LBV)、血浆黏度(PV)、红细胞压积(HCT)、血沉(ESR)及纤维蛋白原浓度(Fc)。结果:观察组产妇产后发现腰背痛、腹痛及恶露不绝各1例,并发症发生率1.90%;对照组产妇产后发现腹痛3例,出血、腰背痛及恶露不绝各2例,乳汁不下和尿潴留各1例,并发症发生率7.59%;观察组的产后并发症发生率显著低于对照组(χ2=5.669,P=0.017)。治疗前,两组患者的血液流变学指标无统计学差异(t1=1.516、1.320、1.807、0.498、2.265、2.170,P1=0.094、0.083、0.103、0.522、0.061、0.076);治疗后,观察组患者HBV、LBV、PV、ESR及Fc均显著低于对照组(t2=8.462、13.83、9.522、9.243、13.99,P2均=0.000)。结论加味生化汤可改善产妇血液流变性,对于减少气虚血瘀导致的产后并发症有正向作用。

Objective： To explore the application value of Chinese traditional medicine Shenghua Tang in postpartum nursing by the analyses of hemorheology and postpartum complications. Methods： 316 cases of vaginal delivery women were selected and divided into two groups（ n1 = n2 = 158） randomly. The women in Group Control were given manipulation cheirapsis,on base of which those in Group Observation were given Shenghua Tang. The postpartum complications were compared between groups. At the same time,fasting venous blood of patients were extracted and high blood viscosity（ HBV）,low blood viscosity（ LBV）,plasma viscosity（ PV）,hematokrit（ HCT）,erythrocyte sedimentation rate（ ESR）,fibrinogen contents（ Fc） were detected with fully automatic blood analyzer. Results： There were 1 case backache,1 case bellyache,and 1 case lochiorrhea in Group Observation,with a complication rate of 1. 90%. There were 3 case bellyache,2 cases bleeding,2 cases backache,2 cases lochiorrhea,1 case breast milk stoppage and 1 case uroschesis in Group Control,with a complication rate of 7. 59%. The complication rate of Group Observation was significant lower than that of Group Control（ χ^2= 5. 669,P = 0. 017）. There was no significant difference between groups in hemorheology before nursing,while the HBV,LBV,PV,ESR and Fc of Group Observation were all significantly lower than that of Group Control（ t2= 8. 462,13. 83,9. 522,9. 243,13. 99; P2= 0. 000）. Conclusion： Chinese traditional medicine Shenghua Tang has ability to improve the hemorheology of puerperal and is benefit to reduce the complications.