主成分聚类分析在药品不良反应报告综合质量评价中的应用

Main Component Analysis and Cluster Analysis on Comprehensive Quality of Adverse Drug Reaction Reports

目的量化评价各市药品不良反应报告综合质量情况。方法在2013年度国家药品不良反应监测系统内江西省数据选定关键指标,通过主成分聚类分析,简化数据关系、直观地观察综合质量情况。结果 12个城市聚类成ABCD4组,各组的药品不良反应报告综合质量情况具有不同特征,其中D组报告综合质量高于其他各组,说明吉安市在江西省12城市中药品不良反应报告综合质量最高。结论各城市的药品不良反应报告综合质量情况可通过主成分聚类分析清晰展现,并且能够得出量化得分。

Objective To discuss the thought and method about the establishment of qualifying ADR reports from the ADR units. Methods By the main component analysis and cluster analysis to simplify data, the key index was selected to assess the quality of ADR reports provided by National Adverse Drug Reaction Monitoring System of Jiangxi Province in 2013. Results The ADR reports of D group from Ji＆#39;an city was with the highest quality in all four groups divided by cluster analysis. Conclusion The main component analysis and cluster analysis can be used to qualify the ADR reports from each city by compositive score.