摘要
多糖是由糖苷键结合的糖链,至少要超过10个的单糖组成的聚合糖高分子碳水化合物。多糖广泛存在于生物体内,是实现生命功能的四大基本物质之一。近年来大量研究表明,多糖的毒性小、安全性高,副作用低。通常认为,多糖类物质能直接杀伤肿瘤细胞,或者通过激活免疫受体使机体免疫功能提高,进而抑制肿瘤,起到较好的抗癌瘤效果。通过对多糖的抗肿瘤研究进展进行综述,旨在为临床用药提供参考。
Polysaccharides, widely exist in the higher plants, fungi, algae, bacteria and cell membranes of animal, is one of the four basic substance of life. In recent years, numerous studies have showed that polysaccharides have immuno-regulation and anti-tumor effect. Polysaccharides are used on the adjuvant treatment of cancer, since it can directly kill tumor cells, activate immune receptors and improve immune function. This paper aims to review the study on anti-tumor of polysaccharides.
出处
《中国药物警戒》
2015年第2期96-98,共3页
Chinese Journal of Pharmacovigilance
基金
2011年度苏州市科技发展计划项目(SYSD2011164)
关键词
多糖
抗肿瘤
免疫调节
进展
polysaccharides
anti-tumor
immunoregulation
progress
