血虚证实验动物造模及其证候的检测与评价

Detection and Evaluation of Experimental Animal Models with Blood Deficiency

血虚证是以体表肌肤黏膜组织颜色淡白且全身虚弱为主要表现的一种证型。基于中医学中气血乃人体的基本物质基础,近年来,国内科研工作者将中医学理论与现代医学实验方法相结合研究血虚证的实验动物模型,成效颇丰。本文通过检索中国知识资源总库(CNKI)数据库,撷取近10年来血虚证动物模型构造、检测及评价标准相关文献,以造模原理为分类标准,从中医传统病因、西医病因病理、综合法3个方面总结回顾现今血虚证实验动物主要造模方法及评定指标,并结合比较结果展望其未来的发展趋势。

Blood deficiency is a syndrome that people feel weak and their mucosal skin becomes pale. Based on the theory that qi and blood are the basic materials of human beings, many domestic researchers have combined traditional Chinese medicine theory with methods of modern medical experiments in search of how to make experimental animal models with blood deficiency, and achieved great success in these years. By searching and arranging related research literature published in recent 10 years in CNKI, this article reviewed modeling methods and evaluation criteria in three aspects：traditional Chinese medicine etiology, western etiology and pathology, and comprehensive methods, with a purpose to provide a bright future through the comparison.