Relationship between red blood cell distribution width and intermediate-term mortality in elderly patients after percutaneous coronary intervention

关于在红血房间分发宽度(RDW ) 和在有冠的动脉疾病(CAD ) 的老病人的中间术语的预后之间的关系的 BackgroundLarge 规模临床的研究正在缺乏。因此，这研究在经历了选任的经皮的冠的干预(一种总线标准) 的老病人的中间术语的死亡上调查了 RDW 的效果从 1891 病人 &#x02265 的 .MethodsData；65 岁从 2009 年 7 月经历了选任的一种总线标准到 2011 年 9 月被收集。基于外科手术前的中部的 RDW (12.3%) ，病人被划分成二个组。低 RDW 组(RDW &#x0003c； &#x000a0； 12.3%) 有 899 个案例；高 RDW 组(RDW &#x02265； &#x000a0； 12.3%) 有 992 个案例。二个组的所有原因死亡率是在高 RDW 组的 compared.ResultsPatients 是更可能的与糖尿病女性、伴随，有的更低的血红素水平。吝啬的后续时期是 527 &#x000a0；天。在后续期间， 61 个病人死了(3.2%) 。高 RDW 组的手术后的死亡比低 RDW&#x000a0 的显著地高；组(4.3% 对 2.0% ， P&#x000a0； =&#x000a0； 0.004 ) 。在调整另外的因素以后， multivariate 考克斯回归分析表明外科手术前的高 RDW 显著地与手术后的所有原因死亡被联系(危险比率：2.301， 95% 信心间隔：1.106-4.785， P&#x000a0； =&#x000a0； 0.026 ).ConclusionsIncreased RDW 是在在选任的一种总线标准以后的老 CAD 病人的增加的中间术语的所有原因死亡的一个独立预言者。

Background Large-scale clinical research on the relationship between red blood cell distribution width （RDW） and intermediate-term prognosis in elderly patients with coronary artery disease （CAD） is lacking. Thus, this study investigated the effects of RDW on the intermediate-term mortality of elderly patients who underwent elective percutaneous coronary intervention （PCI）. Methods Data from 1891 patients 〉 65 years old underwent elective PCI from July 2009 to September 2011 were collected. Based on preoperative median RDW （12.3%）, the patients were divided into two groups. The low RDW group （RDW 〈 12.3%） had 899 cases; the high RDW group （RDW 〉 12.3%） had 992 cases. The all-cause mortality rates of the two groups were compared. Results Patients in the high RDW group were more likely to be female and accompanied with diabetes, had lower hemoglobin level. The mean follow-up period was 527 days. During follow-up, 61 patients died （3.2%）. The postoperative mortality of the high RDW group was significantly higher than that of the low RDW group （4.3% vs. 2.0%, P = 0.004）. After adjusting other factors, multivariate Cox regression analysis revealed that preoperative high RDW was significantly associated with postoperative all-cause mortality （hazard ratio： 2.301, 95% confidence interval： 1.106-4.785, P = 0.026）. Conclusions Increased RDW was an independent predictor of the increased intermediate-term all-cause mortality in elderly CAD patients after elective PCI.