盐酸多奈哌齐在老年痴呆治疗中的应用研究

The Applied Research of Donepezil Hydrochloride in Treatment of Alzheimer

目的探究老年痴呆患者采用盐酸多奈哌齐治疗的方法和效果。方法选取2013年1月-2014年4月收治的86例老年痴呆患者进行治疗,随机分组,实验组49例患者采用盐酸多奈哌齐的治疗,对照组37例患者采取基础治疗,观察患者的治疗效果。结果实验组治疗有效率为85.71%,对照组治疗有效率为59.46%。两组患者的治疗效果差异显著,有统计学意义（P〈0.05）。结论老年痴呆患者采用盐酸多奈哌齐的治疗,不良反应少,安全性高,缓解患者的身体症状。

Objective The treatment and efficiency of donepezil hydrochloride in Alzheimer are to be investigated. Methods Choose 86 patients with Alzheimer who are treated in hospital from January 2013 to April 2014 and separate them into control group and study group at random. 49 patients in study group are given donepezil hydrochloride treatment and 37 patients in control group are given elementary treatment. And then observe the treatment efficiency of two groups. Results The treatment efficiency in study group is up to 85.71%and treatment efficiency in control group is up to 59.46%,there is a treatment differential between the two groups,such a differential has statistic value（P〈0.05）.Conclusion Donepezil hydrochloride treatment is quite effective and safe to cure Alzheimer and relieve patients’ symptoms with less side-effect,which is worthy to be promoted and applied.