高血压颈动脉斑块与缺血性脑卒中相关性研究

Correlative Studies on Carotid Atherosclerosis and Ischemic Stroke in Hypertension Patients

目的探讨高血压颈动脉斑块与缺血性脑卒中患病率之间的相关性。方法入选原发性高血压患者120例,以是否伴有缺血性脑卒中分为两组,伴缺血性脑卒中者75例,单纯高血压组45例,彩色多普勒超声检查两组患者的颈动脉斑块的数量、部位、大小和颈总动脉内中膜厚度。结果缺血性脑卒中组与单纯高血压组比较,颈动脉斑块的发生率明显增加(74.67%vs 53.33%,P<0.05),不稳定斑块的比例较高(66.67%vs 31.11%,P<0.05),斑块的部位、大小及颈总动脉内中膜厚度两组无差异(P>0.05),多因素回归分析显示,年龄、糖尿病是颈动脉斑块形成的独立危险因素,颈动脉斑块可增加高血压患者缺血性脑卒中的风险。结论颈动脉斑块与高血压缺血性脑卒中的发生密切相关,是缺血性脑卒中的独立危险因素。

Objective To investigate the hypertension carotid plaque and ischemic stroke prevalence correlation between the rate of. Methods A total of 120 patients with essential hypertension,as to whether or not associated with ischemic stroke were divided into two groups,color Doppler ultrasound of carotid artery plaque number,two groups of patients the position,size and carotid artery intima media thickness. Results The ischemic stroke group compared with the simple hypertension group,apparent increased incidence of carotid artery plaque,plaque size and a higher proportion of total artery,carotid intima media thickness plaque site,no significant difference between two groups （P 〉 0.05）. Conclusion Carotid plaque and hypertensive ischemic stroke is closely related to the occurrence,is an independent risk factor for ischemic stroke.