摘要
目的分析高通量透析膜在血液透析中的作用和效果。方法选取于本院进行血液透析的患者80例,随机分为对照组和实验组,对照组应用低通量透析膜,观察组应用高通量透析膜。观察患者透析前后的血尿素氮、血肌酐、血磷浓度,及β2-微球蛋白含量变化,计算溶质清除率。结果观察组与对照组的血尿素氮、血肌酐、血磷清除率比较无显著差异(P>0.05)。观察组患者透析后血β2-微球蛋白含量比透析前有明显下降,下降率明显高于对照组(P<0.05),具有统计学意义。结论高通量透析膜不仅保持了对小分子毒素的清除能力,且清除中大分子毒素效果显著,能有效减少血液透析并发症,提高患者的生存率和生活质量,值得临床大力推广。
Objective To analysis and the effect of high flux dialysis membranes in hemodialysis effect. Methods Selected in our hospital 80 cases of hemodialysis patients, the control group using low flux dialysis membranes, the observation group application of high flux dialysis membranes. Observation of blood urea nitrogen, blood creatinine, blood phosphorus concentration in patients before and after dialysis, and changes of beta 2- microglobulin, calculate the solute clearance rate. Results The observation group and the control group, the blood urea nitrogen, blood creatinine, blood phosphorus removal rate with no significant difference （P〉0.05）. The observation group patients after dialysis blood beta 2-microglobulin content than the pre dialysis have decreased significantly,the rate of decline was significantly higher than the control group（P〈0.05）, with statistical significance. Conclusion High flux dialysis membranes not only keep on smal molecule toxin scavenging ability, and clear the macromolecular toxin effect significantly, can effectively reduce the complication of hemodialysis, improve the survival rate and quality of life, worthy of clinical popularization.
出处
《中国卫生标准管理》
2015年第4期38-39,共2页
China Health Standard Management
关键词
高通量透析膜
血液透析
治疗
High flux hemodialysis
Hemodialysis
Treatment
