纳洛酮救治新生儿窒息临床疗效观察

To Observe the Clinical Efficacy of Naloxone in Treatment of Neonatal Asphyxia

目的观察并分析纳洛酮救治新生儿窒息的临床效果。方法将我院在2012年7月到2014年7月收治的122例窒息新生儿随机分为观察组和对照组,每组61例。对照组患儿采用常规的治疗方法进行干预救治,观察组患儿在常规治疗基础上配合给药纳洛酮进行救治,观察并比较两组患儿的救治效果。结果观察组的治疗效果明显优于对照组,有效治愈患儿59例,治愈率为96.72%,对照组治愈患儿38例,治愈率为57.38%,两组比较差异显著,P<0.05;观察组所出现的不良反应更少,且并发症发生率较低,患儿家属的满意率更高,综合比较,差异显著,P<0.05。结论在临床上,关于新生儿窒息的治疗,在常规治疗的基础上配合纳洛酮进行干预,能够取得更为显著的效果,可以提高患儿的治愈率,减少并发症的发生,值得在临床推广使用。

Objective To observe the clinical ef ect of naloxone in treatment of neonatal asphyxia and analysis. Methods In our hospital 122 cases of neonatal asphyxia were randomly divided into observation group and control group. The control group were treated by conventional treatment intervention treatment, the 〈br〉 observation group with on the basis of conventional treatment combined with administration of naloxone for treatment, the treatment ef ect were observed and compared between the two groups of children with. Results In the observation group, the therapeutic ef ect was significantly better than the control group, the dif erence between the two groups was significant, P〈0.05; less adverse reaction which occurs in the observation group, and the low incidence of complications, patients＆#39; satisfaction rate is higher, the comprehensive comparison, the dif erence was significant, P〈0.05. Conclusion In clinic, on the treatment of neonatal asphyxia, on the basis of conventional treatment combined with naloxone intervention, to get a more pronounced ef ect, can improve the cure rate of children, reduce occurrence of complications, it is worth in clinical use.