摘要
以α-萘酚为起始原料,经过5步反应得到4-(吡啶-2-甲氧基)-5,6,7,8-四氢萘酚-1-胺,总收率为27%。该制备工艺原料易得、反应条件温和、后处理简单,适合实验室的小规模制备。
4-(Pyridin-2-methoxy)-5,6,7,8-tetrahydro-l-aminonaphthol was synthesized in five-steps using α- naphthol as the starting material, and the overall yield was 27%. The advantages of this improved process included lower prices of commercial starting materials, mild reaction conditions, and suitable for bench-scale production.
出处
《精细化工中间体》
CAS
2015年第1期50-52,56,共4页
Fine Chemical Intermediates