雌、孕激素水平检测与过期妊娠分娩发动的关系

The Relations of Estrogen and Progesterone Levels and Prolonged Pregnancy Onset of Labor

目的：探讨雌、孕激素水平检测与过期妊娠分娩发动的关系。方法选择2003年11月～2004年11月间在本院待产及临产的孕周超过42周的单胎初产妇57例，分为未临产组及临产组，用放射免疫法测定血清及羊水中E2，E3，P的含量。结果血清中E2、E3及E2/P、E3/P值在临产组较未临产组明显增高，差异有极显著性（P＜0.01）；羊水中E2、E2/P值在临产组较未临产组明显增高，差异有极显著性（P＜0.01）；E3、E3/P值在临产组较未临产组增高，差异有显著性（P＜0.05）；P值在临产组较未临产组稍有降低，差异无显著性（P＞0.05）。结论血与羊水中的雌激素水平在临产组较未临产组增高，差异有统计学意义，说明临产后雌激素水平增高对分娩发动有重要意义。

Objective To investigate the relations of estrogen and progesterone levels and prolonged pregnancy onset of labor. Methods 57 cases of the produced and the single births of early maternal gestational whose age were over 42 weeks from November 2003 to November 2004 in our hospital were divided into not labor group and labor group, mensurate content of E2, E3, P in serum and amniotic lfuid were detected by radioimmunoassay. Results The value of E2, E3 and E2/P, E3/P in serum were more increased in the labor group than those in not labor group, the difference was significant （P〈0.01）. The values of E2, E2/P were more increased in the labor group than those in not labor group, the difference was signiifcant （P〈0.01）. The values of E3, E3/P were more increased in the labor group than those in not labor group, the difference was significant （P〈0.05）. P values was more decreased in the labor group than those in not labor group, the difference was not signiifcant （P〈0.05）. Conclusion The levels of estrogen in blood and amniotic fluid are more increased in the labor group than those in not labor group, the difference are statistically signiifcant, indicating that increased levels of estrogen in labor is important to the onset of labor.