益心康泰治疗糖尿病周围神经病变的疗效观察

Clinical Observation of Yinkangtai in the treatment of Diabetic Peripheral Neuropathy

目的观察益心康泰治疗糖尿病周围神经病变的疗效。方法选取我院92例糖尿病周围神经病变患者,随机分成观察组(46例)和对照组(46例),两组均进行基础治疗,对照组采用甲钴胺0.5 mg,每日三次口服,实验组在对照组基础上加用益心康泰,每日三次,每次两粒口服治疗。结果观察组治疗后临床总有效率为91.3%,高于对照组的73.91%,差别具统计学意义(P<0.05);观察组治疗后神经传导速度高于对照组,差异有统计学意义(P<0.05)。结论益心康泰联合甲钴胺治疗糖尿病周围神经病变疗效确切,是糖尿病神经病变特别是合并冠心病患者良好的选择。

Objective To investigate the clinical efifcacy of Yinkangtai for diabetic peripheral neuropathy （DPN）. Methods Clinical data of 92 patients with DPN were collected and divided into treatment group and control group, 46 cases in each group. The control group was administrated with mecobalamin orally on the basis of glucose control, while the treatment group was given Yixinkangtai therapy based on the therapy of control group. After 4 weeks’continuous treatment, the clinical efficacy, nerve conduction velocity （NCV） before and after treatment in both groups were observed and compared. Results The total effective rate was 91.3%（42/46） in the treatment group and 73.91% （34/46） in the control group with statistically signiifcant difference （P〈0.05）. After treatment, the nervus peroneus communis NCV and median NCV in the treatment group were signiifcantly superior to those in the control group （P〈0.05）. Conclusion The clinical therapy of Yixinkangtai has a signiifcant effect in the treatment of DPN, which is a good choice for DPN patients with coronary heart disease.