摘要
目的:探讨乳腺钼靶X射线摄片与血清糖类抗原15-3(CA15-3)、癌胚抗原(CEA)和骨桥蛋白(OPN)联合检测对乳腺癌的临床诊断价值。方法:选择在我院经手术和病理证实为乳腺癌的患者60例作为研究组,另选取60例健康体检者作为对照组。分别检测两组的血清CA15-3、CEA和OPN水平,并采用乳腺钼靶X射线检查。比较X射与血清学检测单独检测及联合检测的阳性率。结果:研究组患者血清CA15-3、CEA及OPN水平均显著高于对照组,差异具有统计学意义(P<0.05);血清CA15-3、CEA、OPN和钼靶X射线摄片联合检测的敏感性显著高于单独检测,差异具有统计学意义(P<0.05)。结论:对乳腺癌患者进行钼靶X射线摄片及肿瘤相关标志物检测可提高阳性检出率,有利于乳腺癌的早期诊断及治疗。
Objective: To investigate the diagnostic value of mammography X-ray radiography and serum detection of carbohy- drate antigen 15-3 (CA15-3), carcinoembryonic antigen (CEA) and osteopontin (OPN) for breast cancer. Methods: 60 cases with breast cancer who were treated in our hospital were selected as the study group, and 60 healthy volunteers were selected as a control group. The two groups were detected in serum CA15-3, CEA and OPN levels and the use of mammography X-ray examination. Comparison of X-ray-positive rate and serology testing and joint detection alone. Results: The study group serum CA 15-3, were significantly higher than CEA and OPN water, the difference was statistically significant(P〈0.05); serum CA15-3, CEA, OPN and mammography X-ray radiogra- phy combined detection significantly higher detection sensitivity alone, the difference was statistically significant (P〈0.05). Conclusion: Radiography and tumor-associated markers for breast cancer patients concluded the X-ray mammography can increase the positive detec- - tion rate for early diagnosis and treatment of breast cancer.
出处
《现代生物医学进展》
CAS
2015年第5期912-914,共3页
Progress in Modern Biomedicine