甲泼尼龙琥珀酸钠早期治疗手足口病的临床分析

Clinical analysis of methylprednisolone sodium succinate in early treatment of hand foot and mouth disease

目的探讨甲泼尼龙琥珀酸钠治疗手足口病的疗效。方法 112例手足口病患儿随机分成对照组和观察组,各56例。对照组给予常规治疗,观察组在常规治疗基础上同时静脉滴注甲泼尼龙琥珀酸钠。比较两组的治疗效果。结果观察组症状消失时间和住院天数少于对照组,差异有统计学意义(P<0.01);观察组总有效率92.86%高于对照组总有效率78.57%,差异有统计学意义(P<0.05)。结论甲泼尼龙琥珀酸钠治疗手足口病疗效显著,值得临床应用。

Objective To investigate the curative effect of methylprednisolone sodium succinate in treatment of hand foot and mouth disease.Methods A total of 112 children with hand foot and mouth disease were randomly divided into control group and observation group, with 56 cases in each group. The control group received conventional treatment, and the observation group received additional intravenous drip of methylprednisolone sodium succinate. Curative effects of the two groups were compared.Results The observation group had shorter symptoms disappear time and hospital stays than the control group, and the difference had statistical significance （P〈0.01）. The total effective rate was 92.86% in the observation group, which was higher than 78.57% in the control group. The difference had statistical significance （P〈0.05）. Conclusion The treatment by methylprednisolone sodium succinate for hand foot and mouth disease has precise effect, and it is worth clinical application.