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MTA-1及PCNA在腺性膀胱炎中的表达及临床意义

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摘要 目的探讨转移相关基因(MTA-1)及增殖细胞核抗原(PCNA)在腺性膀胱炎中的表达和临床意义。方法选取本院膀胱移行细胞癌标本、腺性膀胱炎标本、正常膀胱黏膜标本各20例,使用免疫组织化学方法分别进行检测标本中的MTA-1及PCNA的表达。记录三组标本中MTA-1和PCNA的表达阳性率。结果 MTA-1在三组中的表达阳性率相比较差异有统计学意义(P<0.05),和正常膀胱黏膜比较MTA-1在其他两组中表达的阳性率较高(P<0.05),和膀胱移行细胞癌比较MTA-1在腺性膀胱炎中表达阳性率较低(P>0.05)。PCNA在三组中的表达阳性率相比较差异有统计学意义(P<0.05),在腺性膀胱炎和膀胱移行细胞癌中表达阳性率较高(P<0.05),和膀胱移行细胞癌比较在腺性膀胱炎中表达阳性率较低(P<0.05)。结论 MTA-1及PCNA的表达在膀胱肿瘤中具有十分重要的意义,对膀胱炎的性质和发展具有预测功能。
作者 刘旭
出处 《中国实用医药》 2015年第3期71-72,共2页 China Practical Medicine
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