阿托伐他汀钙治疗血管性痴呆的临床疗效

Clinical Analysis of vascular Dementia Treatment with Atorvastatin

目的探讨阿托伐他汀钙治疗血管性痴呆的临床疗效及安全性。方法选取我院收治的血管性痴呆患者78例,随机将其分为两组,对照组患者采取常规药物治疗,治疗组患者在此基础上加用阿托伐他汀钙治疗;比较两组患者临床治疗效果。结果治疗前,两组患者简易智能状态量表(MMSE)、日常生活能力量表(ADL)及长谷川痴呆量表(HDS)评分比较,差异无统计学意义(P>0.05);治疗后,治疗组患者的MMSE评分、ADL评分、HDS评分均优于对照组,差异有统计学意义(P<0.05)。结论阿托伐他汀钙治疗血管性痴呆的临床疗效明显,可改善患者的认知功能,提高患者生活能力和生活质量。

Objective To investigate the clinical efficacy and safety of atorvastatin calcium in the treatment of vascular dementia.Methods 78 patients with vascular dementia were treated in our hospital were selected, and were randomly divided into two groups,The control group taking conventional medication,the treatment group based on the use of atorvastatin treatment;clinical outcomes were compared.Results Before treatment,both groups MMSE score,ADL score,HDS score difference was not statistically significant（P〉0.05）;After treatment,the treatment group MMSE score,ADL score,HDS score than the control group,there are statistical differences between groups significance（P〈0.05）.Conclusion Atorvastatin treatment of vascular dementia clinical efficacy significantly,can significantly improve patients＇ cognitive function,improve the capacity and quality of life of patients living worthy of promotion and application.