内科重症监护病房耐药鲍曼不动杆菌流行病学分析

Medical ICU Resistant Acinetobacter Baumannii Epidemiological Analysis

目的探讨内科重症监护病房(MICU)耐药鲍曼不动杆菌流行病学。方法收集2011年1月至2013年12月MICU送检的菌株标本637株,进行菌株分离鉴定及药敏试验,再行细菌菌谱及耐药性分析。结果 3年来分离出的鲍曼不动杆菌株占所有分离菌株总数的40.0%。除了替加环素,鲍曼不动杆菌几乎对所有抗生素的耐药率在70.0%以上,且有逐年增加的趋势;对碳青霉烯类耐药率达95.0%以上。结论 MICU鲍曼不动杆菌是主要流行病菌,其耐药率极高,除了鲍曼不动杆菌本身的属性外,还与交叉感染、消毒隔离及抗生素的应用有关。

Objective To explore the Department of internal medicine,ICU（MICU） resistant Bauman real epidemiological situation and reasons of bacillus.Methods 2011 January to 2013 December were collected for specimens of 637 strains of MICU isolates,for strain identification and drug sensitivity test,re analysis and drug resistance of bacteria.Results Separation of 3 years of Bauman Acinetobacter strains accounted for 40% of the total number of all isolates. In addition to tigecycline,Bauman Acinetobacter resistance to almost all antibiotics rate was more than 70%,and there is an increasing trend year by year; of carbapenem resistance rate of more than 95%.Conclusion MICU Bauman Acinetobacter is a major epidemic pathogen,and the resistant rate is extremely high,in addition to Bauman real property Bacillus itself,but also with the cross infection,disinfection and isolation and antibiotic application related.