星状神经节阻滞联合丁咯地尔治疗椎动脉型颈椎病的临床观察

Clinical observation of stellate ganglion block combined buflomedil in vertebral artery type of cervical syndrome

目的观察星状神经节阻滞联合丁咯地尔治疗椎动脉型颈椎病(CSA)的临床效果。方法将120例CSA患者分为研究组与对照组,每组60例。研究组给予神经节阻滞联合丁咯地尔静脉注射治疗,对照组单纯采用丁咯地尔静脉注射治疗。测定并比较两组治疗前后椎动脉和基底动脉平均血流速度,观察两组患者治疗效果。结果治疗后,研究组总有效率为95.00%显著高于对照组的71.67%,差异有统计学意义(χ2=24.474,P<0.05)。两组治疗后的椎动脉血流速度较治疗前均明显提升,差异有统计学意义(均P<0.05);研究组椎动脉血流速度为(38.44±2.20)cm/s明显高于对照组的(34.36±3.50)cm/s,差异有统计学意义(t=7.645,P<0.05)。两组治疗后基底动脉血流速度较治疗前有均明显提升,差异有统计学意义(均P<0.05),研究组治疗后椎动脉血流速度(56.34±4.10)cm/s明显高于对照组的(47.69±3.90)cm/s,差异有统计学意义(t=11.841,P<0.05)。结论星状神经节阻滞联合丁咯地尔治疗椎动脉型颈椎病临床疗效明显,较单纯采用药物有显著优势,值得进一步推广。

Objective To explore clinical effect of the stellate ganglion block combined buflomedil in the treatment of vertebral artery type of cervical syndrome（CSA）.Methods One hundred and twenty cases of CSA were included in the study,and randomly divided into two groups.Study group（60cases）patients were treated by stellate ganglion block therapy combined with buflomedil intravenous;the controlled group（60cases）was treated with buflomedil intravenous therapy only.In the treatment,vertebral-basilar artery mean flow velocity（Vm）was measured before and after treatment and comparison of Vm difference was the clinical basis.According to the CSA standard of clinical cure,the clinical curative effect was observed.Results After treatment,the total effective rate of study group was 95.00%,total effective rate of control group was 71.67%,the difference statistically significant（χ2=24.474,P〈0.05）.vertebral artery blood flow velocity of the two groups after treatment increased more obvious than that of before treatment,the difference was statistically significant（P〈0.05）,vertebral artery blood flow velocity after treatment of study group（38.44±2.20）cm/s was significantly higher than that of the control group（34.36±3.50）cm/s,the difference was statistically significant（t=7.645,P〈0.05）.basilar artery blood flow velocity of the two groups after treatment increased more obvious than that of before treatment,the difference was statistically significant（P〈0.05）,basilar artery blood flow velocity after treatment of study group（56.34±4.10）cm/s was significantly higher than that of the control group（47.69±3.90）cm/s,the difference was statistically significant（t=11.841,P〈0.05）.Conclusion The clinical efficacy of stellate ganglion block combined buflomedil in treatment of vertebral artery type of cervical syndrome is obvious.The cure rate with respect to the drug treatment has significant advantages and the therapy is worthy of further promotion.