2001~2011年石河子地区COPD住院患者合并高血压和糖/脂代谢紊乱情况调查

Survey on COPD inpatients with hypertension and glucose and lipid metabolism disorders in Shihezi region from 2001 to 2011

目的探讨慢性阻塞性肺疾病（COPD）患者合并高血压和糖/脂代谢紊乱的发病状况及其影响因素。方法选取2001年4月至2011年7月就诊于石河子大学医学院第一附属医院住院的1 376例COPD患者,回顾性分析COPD合并高血压和糖/脂代谢紊乱的发病状况,同时对导致COPD合并高血压和糖/脂代谢紊乱发生的影响因素进行分析。结果 （1）COPD患者中合并高血压、糖尿病/糖耐量异常、高脂血症/脂蛋白代谢紊乱的发病率分别为41.1%、17.2%、9.2%。（2）就合并高血压、糖尿病/糖耐量发病率而言,3个不同年龄段比较,差异均有统计学意义（P〈0.01）;60-〈80岁患者高脂血症/脂蛋白代谢紊乱发病率较40-〈60岁患者更高,差异有统计学意义（P〈0.05）。（3）男性患者中COPD合并高血压、糖尿病/糖耐量异常、高脂血症/脂蛋白代谢紊乱的发病率为36.0%、16.5%、4.8%,女性患者中该比率分别为47.6%、22.3%、10.8%,两组比较,差异均有统计学意义（P〈0.01）。（4）50-〈60岁、60-〈70岁女性患者的高血压患病率较男性高,差异均有统计学意义（P〈0.05）,其中以60-〈70岁阶段差异最为显著。随着年龄的增大,女性患者高脂血症/脂蛋白代谢紊乱发病率较男性高,在70-〈80岁阶段最为明显,差异有统计学意义（P〈0.05）。结论年龄和性别均能影响COPD合并高血压和糖/脂代谢紊乱的发生,为临床上预防和治疗COPD合并症提供理论指导。

Objective To approach the morbidity and the influencing factors of hypertension and glucose/lipid metabolism induced by chronic obstructive pulmonary disease（COPD）. Methods A retrospective prevalence survey on 1 376 COPD inpatients with hypertension and glucose and lipid metabolism disorders from April 2001 to July 2011 in the First Affiliated Hospital,Medical Hospital of Shihezi University was conducted,whose influencing factors were analyzed correlatively. Results（1）The incidence rates of COPD patients with hypertension,glucose/lipid metabolism,hyperlipemia/lipoprotein metabolism disorders were respectively 41.1%,17.2%,9.2%.（2）Referring to the hypertension,incidence of diabetes and glucose tolerance,there was statistical significance between the difference age sections（P〈0.01）;the incidence of hyperlipemia/lipoprotein metabolism disorders in the patients aged 60-〈80 years old was higher than that of ones aged 40-〈60 years old. It was statistically significant in difference（P〈0.05）;（3）The incidence rates of the male COPD patients with hypertension,glucose/lipid metabolism,hyperlipemia/lipoprotein metabolism disorders were 36.0%,16.5%,4.8% respectively. The incidence rates of the female COPD patients with hypertension,glucose/lipid metabolism,hyperlipemia/lipoprotein metabolism disorders were 47.6%,22.3%,10.8% respectively. The two groups had statistical significance in difference（P〈0.01）.（4）The prevalence of the female patients with hypertension aged 50-〈60,60-〈70 years old was higher than that of the male patients,whose difference was statistical significant（P〈0.05）. hose difference aged 60-〈70 years old was most remarkable. The difference was statistically significant（P〈0.05）. With increasing of the age,the female patients were higher than that of the male ones in prevalence of hyperlipidemia/lipoprotein metabolism,especially aged 70-〈80,whose difference had statistical significant（P〈0.05）. Conclusion Both age and gender can affect the incidence of COPD patients with high blood pressure and glucose/lipid metabolism disorder,and that provide theoretical guidance for the clinical complications prevention and treatment of COPD.