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Notch信号通路在心脏干/祖细胞中的研究进展

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摘要 Notch信号通路存在于机体细胞与细胞之间的复杂网络中,参与多种细胞的形成过程:如细胞分化、激活、凋亡/存活和增殖等,相邻的细胞可通过Notch配体与受体结合传递Notch信号,从而扩大并固化细胞间的分子差异,最终决定细胞命运[1]。由于心肌细胞的再生能力有限,各种原因致心肌坏死后愈合形成纤维化瘢痕,导致心功能进行性下降。
作者 郑小宇 石蓓
出处 《现代医药卫生》 2015年第5期707-710,共4页 Journal of Modern Medicine & Health
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