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IgA肾病中西医诊疗进展 被引量:3

Advantages of Chinese and Western Medicine in Treatment and Diagnosis of Ig A Nephropathy
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摘要 Ig A肾病是最常见的原发性肾小球肾炎,目前西医研究主要涉及Ig A分子、免疫机制、遗传基因及因子表达等,但具体发病机制尚未阐明,近年来主要在糖基化缺失、基因分子等方面取得较大进展;中医研究集中在辨证分型、专方经验等方面,其中在中医证型与肾脏微观病理关系取得一定成果,但尚未完全统一。 Ig A nephropathy is the most common primary glomerulonephritis. Currently,Western medicine research involves molecular,immunological mechanisms,genetic and expression and other factors,but the exact pathogenesis has not been elucidated. In recent years,there is great progress mainly in glycosylation lack,molecular gene,etc. Chinese medicine research has focused on syndrome differentiation,post-party experience and so on,which made some achievements in syndromes and renal microscopic pathology relations,but not yet fully unified.
出处 《辽宁中医药大学学报》 CAS 2015年第3期104-107,共4页 Journal of Liaoning University of Traditional Chinese Medicine
基金 基金项目:北京中医药大学自主选题
关键词 IGA肾病 中西医 最新进展 Ig A nephropathy TCM and Western medicine latest progress
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参考文献38

  • 1王海燕.肾脏病学[M].3版.北京:人民卫生出版社,2008:8262.
  • 2Locatelli F,Yecchio LD,Pozzi C.IgA glomerulonephritis:beyond angiotensin-converting enzyme inhibitors[J].Nat Clin PractNephrol,2006,2(1):24-31.
  • 3Renfrow MB.Determination of aberrant O-glycosylation in the IgA1 hinge region by electron capture dissociation fourier transformion cyclotron resonance mass spectrometry[J].J Biol Chem,2005,280(19):19136-19145.
  • 4Novak J.IgA1-containing immune complexes in IgA nephropathy differentially affect proliferation of mesangial cells[J].Kirlney Int,2005,67(2):504-513.
  • 5Vander Boog P J,van Kooten C,van Seggelen A,et al.An increased polymeric IgA level is not a prognostic marker for progressive IgA nephropathy[J].Nephrol Dial Transplant,2004,19(10):2487-2493.
  • 6Itoh A,I wase H,Takatani,et al.Tonsillar IgAl as a possible source of hypoglycosylated IgA1 in the serum of IgA nephropathy atientsp[J].Nephrol Dial Transplant,2003,18(6):1108-1114.
  • 7SAKAGUCHI S,SAKAGUCHI N,ASANO M,et al.Pillars article:immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chain(CD25).Breakdown of single mechanism of self-tolerance causes various autoimmune Hisease[J].J Immunol,2011,186(7):3808-3821.
  • 8HUANG H,PENG Y,LIU H,et al.Decreased CD:CD25+ cells and increased dimeric IgA -producing cellsin tonsils in IgA nephropathy[J].Nephrol,2010,23(2):202-209.
  • 9肖俊,朱玲燕,陈崴,聂静,陈文芳,董秀清,彭文兴,黄锋先,余学清.调节性及辅助性T细胞在人类IgA肾病中的表达及意义[J].中华肾脏病杂志,2008,24(8):544-549. 被引量:12
  • 10Li G S,Zhu li,Zhang H,et al.Variants of the ST6GALNAC2 promoter transcriptional activity and contribute to genetic susceptibility to IgA nepropathy[J].Hum Mutat,2007,28(10):950-957.

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