永存颈内-基底动脉合并多发脑梗死临床特点分析

Clinical features of persistent carotidbasilar artery associated with multiple cerebral infarction

目的探讨永存颈内-基底动脉合并多发脑梗死的脑循环及临床特征。方法选择经CT、磁共振弥散加权成像、数字减影血管造影、磁共振血管造影或CT血管造影确诊的永存颈内．基底动脉合并多发脑梗死患者5例，回顾性分析其临床资料、病因分型及发病机制。结果5例患者均存在多发脑梗死，有发作性头晕表现，其中2例合并一侧肢体活动不利。4例患者存在永存三叉动脉，1例患者存在永存舌下动脉。病因分型均为大动脉粥样硬化型，发病机制为动脉-动脉栓塞。结论永存颈内-基底动脉改变了正常脑循环，与所合并多发脑梗死的发病机制相关。

Objective To explore the cerebral circulation characteristics and clinical features of persistent carotid-basilar artery complicated with multiple cerebral infarction. Methods Clinical data of five patients with persistent carotid-basilar artery complicated with multiple cerebral infarction confirmed by CT, diffusion weighted imaging, digital subtraction angiography, magnetic resonance angiography or CT angiography were retrospectively analyzed. The clinical materials, stroke etiological subtype and pathogenesis were analyzed. Results All the five patients had multiple cerebral infarction with paroxysmal dizziness and 2 of them had one-side weakness. There were 4 with persistent trigeminal artery and 1 with persistent hypoglossar artery. The stroke etiological subtypes of all the five patients were large-artery atherosclerotic cerebral infarction and the pathogenesis was artery- to-artery embolism. Conclusions The normal cerebral circulation is changed by persistent carotid-basilar artery, which is related with the pathogenesis of multiple cerebral infarction.