慢性消化性溃疡生命质量及患者报告结局的影响因素分析

The quality of life in patients with chronic peptic ulcer and its influence factors

目的对慢性消化性溃疡(PU)患者进行生命质量测评,分析影响患者生命质量的因素。方法采用普适性量表——健康状况调查问卷(SF-36)作为调查工具,对120例PU住院患者生命质量进行测评。利用两独立样本t检验对患者的生命质量得分和全国常模进行比较。利用两独立样本t检验和方差分析,分别对不同性别、年龄、民族、职业、婚姻、医疗形式、经济状况、文化程度、治疗方法、临床类型的各领域得分进行比较分析。结果 PU患者除了精神健康(MH)领域之外其余7个领域以及躯体综合总分(PCS)、心理综合总分(MCS)得分均低于健康对照组,差异有统计学意义(P<0.05);性别、年龄、经济状况、文化程度、医疗形式和治疗方法对SF-36量表某些领域或者综合总分有影响,差异均有统计学意义(P<0.05)。结论找出影响PU患者生命质量的因素,为今后临床治疗提供基础。

Objective To analyze the quality of life and its influence factors in patients with peptic ulcer. Methods The SF- 36 was used to survery 120 patients with peptic ulcer. The QOL scores at different levels of some factors including gender,age,na- tionality, occupation, marriage, medical forms, economic, cultural level, treatment method and clinical type were compared by meth- ods of two sample t-test and analysis of variance. Results Peptic ulcer patients＇ scores in the domain of RE,PF,RP,BP,GH,VT, SF,RE, PCS and MCS are lower than that of the normal~ exception of the domain of MH（P〈0.05）. The differences wege statisti- cally significant. Six factors can be influenced some domain or total score of the scale（P〈0.05）and the differences were statistical- ly significant. Conclusion Find out the influencing factors on peptic ulcer patients＇ quality of life can be provided the basis for clini- cal treatments.