恩施州精神分裂症患者复发的危险因素研究

Study on Risk Factors of Relapse of Schizophrenia in Enshi Area

目的探讨精神分裂症患者复发的相关危险因素。方法以2008-2010年恩施某医院精神分裂症病例218例为研究对象,随访1年内基本情况、临床相关资料,进行多元Logistic回归分析。结果单因素分析显示,年龄、情绪波动、婚姻、熬夜、治疗依从性、家庭关怀、社区精神卫生服务、家庭经济状况、儿童期创伤史、饮酒史、社区精神分裂症家族史与复发相关。多因素回归分析显示,复发的危险因素有情绪波动、熬夜、治疗依从性、家庭关怀、精神卫生服务、家庭经济状况、儿童期创伤史、饮酒史、精神分裂症家族史,而已婚为保护因素。结论精神分裂症复发与多因素相关,缺乏家庭关系、缺少有效的社区精神卫生服务支持、家庭经济状况差等是复发的危险因素。

Objectives To explore the risk factors of relapse of schizophrenia.Methods 218 schizophrenia patients from2008 to 2010were enrolled to carry out the risk factors analysis.All the patients were followed up for 1year to collect the basic information and the clinical relevant information.The data was analyzed by logistic regression model.Results The results of the univariate analysis showed that 13 factors were associated with the relapse of schizophrenia,including age,mood swings,stay up late,marital status,family support,community mental health service,treatment compliance,economic status of family,drinking history,trauma history in children and family history of schizophrenia.The results of the multi-factor regression analysis showed that emotional fluctuation,stay up late,treatment compliance,family support unavailable,community mental health service unavailable,poor economic status of family,trauma history in children,drinking history,family history of schizophrenia were risk factors of the relapse of schizophrenia,while being married was protective factor.Conclusions Family support unavailable,community mental health service unavailable,poor economic status of family etc.are risk factors for the relapse of schizophrenia.