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子宫内膜树突状细胞的免疫组织化学研究

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摘要 目的研究人正常子宫内膜上树突状细胞(dendritic cell,DC)的分布特点。方法对77例人正常子宫内膜组织(增殖期内膜、分泌期内膜各32例,绝经期内膜13例)应用HLA-DR单克隆抗体和CD1a蛋白抗体进行免疫组织化学染色分析。结果 32例增殖期、32例分泌期和13例绝经期子宫内膜的HLA-DR阳性表达率分别为65.63%、43.75%和7.69%,CD1a阳性表达率分别为59.38%、46.88%和0.00%。增殖期、分泌期子宫内膜组织HLA-DR和CDIa的阳性表达率均高于绝经期子宫内膜组织(均P<0.05);增殖期和分泌期子宫内膜组织的HLADR和CDIa阳性表达率比较差异无统计学意义(P>0.05)。结论增殖期和分泌期子宫内膜组织HLA-DR和CDIa的阳性率均高于绝经期子宫内膜组织。
作者 陈进 龚沂
出处 《南昌大学学报(医学版)》 CAS 2014年第12期77-78,81,共3页 Journal of Nanchang University:Medical Sciences
基金 江西省卫生厅科技计划(20061066)
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