产后抑郁症危险因素的Meta分析

A Meta-analysis of risk factors of postpartum depression

目的：探讨产后抑郁症发生的危险因素，为制定产后抑郁症的预防控制措施提供科学依据。方法收集国内2003－2013年公开发表的有关产后抑郁症发病危险因素的研究文献，应用RevMan5．2软件进行M eta分析，根据异质性检验的结果选择相应效应模型进行数据合并，计算各危险因素合并比值比（ OR ）及其95％可信区间（ CI ）。结果产后抑郁症各个危险因素的合并 OR值（95％ CI ）分别为经济状况差3.283（2.249～4.792）、与丈夫或公婆关系差2．469（1．855～3．286）、产妇性格内向1．541（1．162～2．044）、孕期有焦虑或抑郁情绪5．925（4．862～7．220）、分娩过程不顺利2．248（1．732～2．918）、产后睡眠质量差2．352（1．935～2．859）、新生儿性别不满意2．133（1．568～2．902）、新生儿健康状况差3．657（2．351～5．689）。结论应从国家加大投入、家庭提供支持、医生加强宣教、孕妇转变观念等方面来预防产后抑郁症的发生。

Objective To investigate the risk factors of postpartum depression and to provide evidence for the prevention and control measures .Methods Domestic published research literatures in 2003—2013 about the risk factors of postpartum depression were collected .Based on the results of heterogeneity tests ,the appropriate data model was selected and the combined odds ratio OR for each risk factor and 95% confidence intervals （CI）is calculated using RevMan 5 .2 Meta‐analysis software.Results The combined OR value （95% CI ） of each risk fac‐tor for postpartum depression were poor economic situation 3 .283（2 .249～4 .792） ,poor relationship with their husbands or in‐laws 2 .469 （1 .855～3 .286） ,introverted personality 1 .541 （1 .162～2 .044） ,anxiety or depression during pregnancy 5 .925 （4 .862～7 .220） ,the unsmooth delivery process 2 .248 （1 .732～2 .918） ,poor postpar‐tum sleep quality 2 .352 （1 .935～2 .859） ,dissatisfaction of neonatal sex 2 .133 （1 .568～2 .902） and poor health condition of newborn 3 .657 （2 .351～5 .689） .Conclusion According to research results ,there should be more in‐vestment from the state ,more support from the family ,and more education from the clinicians ,and pregnant women should change their concepts to prevent the occurrence of postpartum depression .