新生儿先天性消化道闭锁161例临床分析

Clinical analysis of 161 cases of digestive tract atresia

目的探讨新生儿先天性消化道闭锁的部位、临床特点及预后。方法回顾分析中山市博爱医院新生儿科2005年5月至2014年1月期间新生儿科161例消化道闭锁病例的临床资料及其随访结果。结果 161例病例中,食管闭锁35例、肠闭锁53例、肛门闭锁77例。食管闭锁、肠闭锁和肛门闭锁的手术存活率分别为72.7%、85.7%和88.7%,超声检出率分别为16.7%、28.2%和10%。45.7%食管闭锁、35.8%肠闭锁和28.6%肛门闭锁患儿合并其他先天畸形。结论先天性消化道闭锁是新生儿时期常见的消化道畸形,早诊断、早手术是预后关键。消化道闭锁的产前超声检出率不高。消化道闭锁,特别是食管闭锁,合并其他先天畸形的比例较高。

Objective Exploring the position, clinical characteristics and prognosis of digestive tract atresia. Method The clinic data of 161 cases with congenital digestive tract atresia was retrospectively an- alyzed, the data obtained from Neonatology of Boai hospital of Zhongshan during May 2005 to January 2014. Results All the 161 cases including 35 cases of esophageal atresia, 53 cases of intestinal atresia and 77 cases of anal atresia. For three kinds of digestive tract atresia, surgery survival rates were 72.7%, 85. 7% and 88.7%, the Ultrasound detection rates were 16.7%, 28.2% and 10%, and the rates of newborn with other congenital malformations were 45.7%, 35.8% and 28.6 %. Conclusions Congenital digestive tract atresia is a common gastrointestinal malformations, early diagnosis and surgery is critical for progno- sis. The prenatal ultrasound detection rates of congenital digestive tract atresia is still low. Gastrointesti- nal aresia, sepecially esophagus atresia, merging high proportion of other congenital malformations.