脑干急性梗死与小脑上脚交叉弥散高信号的表观弥散系数的对比研究

The comparative study of apparent diffusion coefficient values between brainstem infarction and decussation of superior cerebellar peduncle with high signal intensity on diffusion-weighted imaging

目的：比较脑干急性梗死与正常小脑上脚交叉弥散高信号的表观弥散系数（ADC）值。方法收集经临床诊断并MRI证实的脑干梗死100例，其中急性期组53例（发病时间＜2 d）、亚急性期组47例（发病时间2～14 d）。对照组即正常小脑上脚交叉弥散呈高信号40例。采用磁共振弥散加权成像测定各组受检者 ADC 值。结果脑干急性期、亚急性期梗死灶的 ADC 值分别为（344.72±73.96）×10-6 mm2/s、（425.62±92.86）×10-6 mm2/s，对照组小脑上脚交叉区ADC值为（682.02±36.83）×10-6 mm2/s。经统计学处理，各组 ADC值具有统计学差异（P＜0.001）。结论 ADC值对鉴别脑干急性梗死与正常小脑上脚交叉弥散高信号具有重要的临床价值。

Objective To compare with the apparent diffusion coefficient （ADC） values between brainstem infarction and decussation of superior cerebellar peduncle （DSCP） with high signal intensity on diffusion-weighted imaging （DWI）. Methods All 100 brainstem infarction patients were confirmed by clinical diagnosis and magnetic resonance imaging （MRI）, fifty-three cases were in the acute stage group （the time course less than 2 days） and 47 cases in the subacute stage group （the time course from 2 days to 14 days）. The control group had 40 cases with high signal intensity in the DSCP on DWI. The ADC values of patients in each group were determined using DWI. Results The ADC value of patients in the acute stage group, subacute stage group and control group were （344.72±73.96）×10-6 mm2/s, （425.62±92.86）×10-6 mm2/s and （682.02±36.83）×10-6 mm2/s, respectively. There were significant differences in the ADC values among three groups （P〈0.001）. Conclusion ADC values played an important role in differentiating acute brainstem infarction and DSCP with high signal intensity on DWI.