浙江省成年人群生活方式与血脂异常的相关性研究

Correlation analysis of lifestyle and dyslipidemia among adults in Zhejiang

目的分析浙江省成年人群血脂水平及与生活方式的相关性,为血脂异常防治提供科学依据。方法采用多阶段分层整群随机抽样的方法,按经济发展水平及类型将浙江省90个县（市、区）分成2类城市和3类农村共5类地区,每类地区抽取3个县/区,每个县区随机抽取4个街道/乡镇,每个街道/乡镇随机抽取3个村/居委会,共调查15个样本县（市、区）7 222户样本家庭中年龄18周岁及以上的常住人口（近半年内在该家庭户居住6个月以上的居民）,纳入分析的有效样本量为17 437人,对其进行问卷调查和血脂检测,分析吸烟、饮酒行为和体力活动对血脂的影响。结果调查对象血脂异常患病率为48.00%（8 369/17 437）,其中高甘油三酯血症的患病率为13.02%（2 271/17 437）,高胆固醇血症的患病率为2.53%（442/17 437）,低高密度脂蛋白血症的患病率为41.49%（7 234/17 437）。多因素logistic回归分析结果显示,甘油三酯（TG）与BMI和重度吸烟（≥20支/d）呈正相关;总胆固醇（TC）与体质指数（BMI）、适量身体锻炼（150-420min/周）、职业活动强度、吸烟（〈20支/d）有关;高密度脂蛋白胆固醇（HDL-C）与BMI、职业活动强度、吸烟、饮酒有关。结论控烟限酒、适量体力活动、积极控制体重等生活方式的转变是控制血脂水平的重要方法。

Objective To explore the correlation of lifestyle and dyslipidemia among adults in Zhejiang, so as to provide a scientific basis for prevention and treatment of dyslipidemia. Methods A stratified multistage clus ter sampling method was used to randomly select 17 437 adult residents aged over 18 years from 15 counties in Zhejiang. A questionnaire survey was conducted and blood samples were also collected for the nleasurement of lipid level. Results The overall adjusted prevalence of dyslipidemia was 48.00%, with the prevalence of high triglyceride, high cholesterolemia and low high density lipoprotein of 13.02%, 2.53% and 41.49%, re spectively. Multivariate logistic regression analysis revealed that BMI and heavy smoking （more than 20 cigarettes a day） were positively correlated with high triglycerides （TG）; while, BMI, physical exercise （150 420 minutes a week）, occupational intensity, smoking and drinking were closely related to total cholesterol （TC） and high density lipoprotein （HDL-C） as well. Conclusions Programs on integrated lifestyle modifi cations including no smoking, limited alcohol, moderate exercise and weight control are critical for the control of dyslipidemia.