早期肠内肠外营养支持对结直肠癌患者术后影响

Early postoperative enteral nutrition compared with parenteral nutrition in patients with colorectal cancer

目的比较不同营养支持途径对结直肠癌患者术后营养指标的影响。方法回顾性分析自2010年1月至2014年1月84例胃癌和结直肠癌根治术后患者的临床资料,其中肠内营养组(EN组)43例和肠外营养组(PN组)41例,分别于术后第1天开始进行肠内和肠外营养,2组患者基本等氮、等热量;每组患者手术前后和术后第7天检测血清白蛋白(ALB)、转铁蛋白(TF)、前白蛋白(PA),观察术后不良反应、胃肠道功能恢复时间、感染、营养支持费用等情况。结果术后EN组和PN组的营养指标和不良反应发生率比较无显著性差异(P>0.05);EN组感染发生率低(P<0.01)且胃肠道功能恢复时间早(P<0.01),与PN组相比较差异具有统计学意义。结论结直肠癌患者术后采用肠内营养方案,不良反应少、胃肠道功能恢复快。

Objective To analyze the effect of different postoperative nutrition：enteral nutrition（ EN） and parenteral nutrition（ PN） in patients with colorectal cancer. Methods 84 patients with colorectal cancer were collected in this study from Jan. 2012 to Jan. 2014, and they were divided into the EN group （43 cases） and the PN group （41 cases）. They were given EN or PN after operation. The nutritional parameters such as ALB, TF and PA were detected before surgery and 7 days after operation, Observe the adverse reaction, time of gastroin-testinal function recovery, infection and costs after operation. Results There was no statistical difference （P〉0. 05） in the nutritional pa-rameters and rate of adverse reaction between the two groups. The rate of infection in EN group was lower than that in PN group（P〈0. 01）, and the time of gastrointestinal function recovery was shorter in EN group compared with that in PN group （P〈0. 01）. Conclusion EN is better in recovery of gastrointestinal function, and there is less complication compared to PN. EN have clinical application value for patients with gastrointestinal cancer.