胃肠病患者血清与尿液中一氧化氮含量测定及临床意义

CHANGES OF CONCENTRATION OF NITRIC OXIDE AND ITS CLINICAL SIGNIFICANCE IN PATIENTS WITH GASTROENTEROPATHY

探讨胃肠病患者血清及尿液中一氧化氮 (NO)水平的变化及临床意义。方法 :收集胃肠病患者血清及尿液 ,分别检测其NO水平 ,并进行分析。结果 :急慢性胃炎及急慢性肠炎患者血清及尿液中NO水平明显高于正常健康组 ;胃癌及肠癌者血清及尿液中NO明显降低。结论 :胃肠炎患者NO含量明显增高 ,且NO增高对胃肠起损害作用 ;胃肠癌患者NO含量明显降低 ,且降低水平与病情相关。

Objective:To investigate the clinical significance of the concentration of nitric oxide (NO) in blood and urine in patients with gastroenteropathy. Methods:The concentration of NO was investigated and the mechanism of their changes were analyzed in sera of patients with gastroenteropathy. Results:The results showed that the concentration of NO was significantly increased in gastroenteritis patients compared to normal people. The concentration of NO was lower in patients with gastroenteric cancer than that in normal people. Conclusions:The study indicated that the concentration of NO was significantly increased in gastroenteritis patients; the increase of NO concentration played a role in hurt of gaster and intestine. The study indicated that decreased concentration of NO was related to states of illness in patients with gastroenteric cancer.