蛋白饮食量化对腹膜透析患者生活质量的影响

Effect of protein quantified diet on quality of life in patients with peritoneal dialysis

目的：观察不同蛋白饮食含量对腹膜透析（PD）患者生活质量的影响。方法：67例PD患者随机分为低蛋白组、中蛋白组和高蛋白组,实际完成56例,其中低蛋白组17例、中蛋白组20例、高蛋白组19例。各组患者均实施饮食干预,低蛋白组的蛋白质摄入量〈0.8g/（kg·d）,中蛋白组的蛋白质摄入量0.8-0.12g/（kg·d）,高蛋白组的蛋白质摄入量〉0.12g/（kg·d）。连续随访6个月,采用KDQOL-SFTM1.3量表作为调查工具进行随访前后的生活质量调查,并进行统计分析。结果：干预前后各维度评分相比较,中蛋白组和高蛋白组在SF-36评分及其所属的生理健康、心理健康维度,以及KDTA评分及其所属的症状与不适、肾病对日常生活影响、工作状况、睡眠、社会支持、医护人员鼓励、患者满意度、总体健康评估,及量表总评分方面均有显著差异（P〈0.05）。干预后组间比较,中蛋白组和高蛋白组的SF-36评分及其所属的生理健康维度,以及KDTA评分及其所属的症状与不适、肾病对日常生活影响、工作状况、睡眠、医护人员鼓励、总体健康评估,及量表总评分方面均较低蛋白组有显著改善（P〈0.05）;而中蛋白组除在肾病给生活带来负担维度的改善作用不如高蛋白组外,其余各维度的改善程度与高蛋白组均无显著差异（P〈0.05）。结论：PD患者每日蛋白摄入量控制在0.8-0.12g/（kg·d）即可维持较高的生活质量,其获益程度与高于0.12g/（kg·d）蛋白摄入量的患者一致。

Objective： To observe the influence of different dietary protein content on peritoneal dialysis（PD） the patients＇ life quality. Methods： 67 cases of PD were randomly divided into low protein group, protein group and high protein group,the actual completion of 56 cases, including 17 cases were low protein group, the protein in the group of 20 cases, 19 cases were high protein group. The patients in each group to implement the diet intervention, 〈0.8g/ protein intake of low protein group（kg, d）, the protein in the group of protein intake to 0.8 - 0.12g/（kg, d）, 〉0.12g/ protein intake of high protein group（kg, D）. Continuous followup 6 months, with the KDQOL-SFTM1.3 scale as investigative tools to investigate the quality of life before and after the follow-up, and statistical analysis. Results： each dimension score before and after intervention in comparison, protein group and high protein group in the SF-36 score and its physiological health, psychological health dimension, and the KDTA score and their symptoms and discomfort, nephropathy impact on daily life, work, sleep status, social support, encourage, the satisfaction of patients, medical staff general health assessment, significant difference in total score and scale has（P〈0.05）. The intervention group comparison, physical health dimensions protein group and high protein group SF-36 score and belongs to, and the KDTA score and their symptoms and discomfort, nephropathy impact on daily life, work, sleep status, medical staff encouragement, general health assessment, and scale total score were lower protein group was significantly improved（P〈0.05）, while in the protein group in addition to improving the effect to living in nephropathy burden dimensions as high protein group, there was no significant difference in the rest of the improvement degree of each dimension and high protein group（P〈0.05）. Conclusion： PD patients daily protein intake is controlled in 0.8 - 0.12g/（kg·d） can maintain a high quality of life, the gain level and higher than that of 0.12g/（kg d） protein intake of the patients consistent.